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Chromosomes in human sperm

Aneuploidy is the presence of an abnormal number of chromosomes in a cell , for example a human cell having 45 or 47 chromosomes instead of the usual A cell with any number of complete chromosome sets is called a euploid cell. An extra or missing chromosome is a common cause of some genetic disorders. Some cancer cells also have abnormal numbers of chromosomes. Most cases of aneuploidy in the germline result in miscarriage , and the most common extra autosomal chromosomes among live births are 21 , 18 and Most cells in the human body have 23 pairs of chromosomes , or a total of 46 chromosomes.
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Can changes in the number of chromosomes affect health and development?

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Chromosome - Wikipedia

Chromosomes are thread-like molecules that carry hereditary information for everything from height to eye color. They are made of protein and one molecule of DNA, which contains an organism's genetic instructions, passed down from parents. In humans, animals, and plants, most chromosomes are arranged in pairs within the nucleus of a cell. Humans have 22 of these chromosome pairs, called autosomes. Humans have an additional pair of sex chromosomes for a total of 46 chromosomes. The sex chromosomes are referred to as X and Y, and their combination determines a person's sex. Typically, human females have two X chromosomes while males possess an XY pairing.
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10 Facts About Chromosomes

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A chromosome is a long DNA molecule with part or all of the genetic material of an organism. Most eukaryotic chromosomes include packaging proteins called histones which, aided by chaperone proteins , bind to and condense the DNA molecule to maintain its integrity. Chromosomes are normally visible under a light microscope only during the metaphase of cell division where all chromosomes are aligned in the center of the cell in their condensed form.
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