Toxoplasmosis is a disease that results from infection with the parasite Toxoplasma gondii. In the eye, Toxoplasma infections frequently cause significant inflammation and subsequent scarring which may temporarily or permanently impair vision. Infection can be transmitted through pregnant mothers to their baby congenital or acquired by eating contaminated foods or undercooked meat. Worldwide, toxoplasmosis is the most common cause of inflammation in the back of the eye.
Toxoplasmosis In Dogs: Symptoms, Causes, & Treatments - DogTime
We present a case of the coincidence of progressive multifocal leukoencephalopathy PML and central nervous system CNS toxoplasmosis in an adult patient, without a detectable cause of cell-mediated immunity impairment. The proper diagnosis was made postmortem on the basis of histological changes typical of both pathological processes. PML was characterized by the presence of subcortical focal demyelination, containing enlarged, densely basophilic oligodendrocyte nuclei, often with intranuclear inclusion, and bizarre astrocytes, mimicking neoplastic cells. PML was confirmed by detecting numerous papova virus particles in oligo- and astroglial nuclei by thin-section electron microscopy. Cerebral toxoplasmosis was characterized by the presence of multiple well-circumscribed necrotizing abscesses. Numerous Toxoplasma gondii T. The diagnosis of cerebral toxoplasmosis was further confirmed by immunocytochemistry.
Toxoplasmosis is considered to be a leading cause of death attributed to foodborne illness in the United States. More than 40 million men, women, and children in the U. However, women newly infected with Toxoplasma during or shortly before pregnancy and anyone with a compromised immune system should be aware that toxoplasmosis can have severe consequences. Toxoplasmosis is considered one of the neglected parasitic infections of the United States , a group of five parasitic diseases that have been targeted by CDC for public health action.
Toxoplasmosis is found in humans worldwide and in many kinds of animals and birds. The parasite also lives in cats. Toxoplasmosis also affects people who have weakened immune systems. These people are more likely to have symptoms. The infection may also be passed from an infected mother to her baby through the placenta.